Lactoferrin binds to porins OmpF and OmpC in Escherichia coli
نویسندگان
چکیده
منابع مشابه
Functional role of ompF and ompC porins in pathogenesis of avian pathogenic Escherichia coli.
Avian pathogenic Escherichia coli is an important pathogen causes systemic infections in avian species and large economic losses in poultry industry worldwide. The functional role of porins during the infection and their mechanisms of interaction with host tissues for adhesion to and invasion are poorly understood. However, whether porins play a role in infection remains unclear. In this study ...
متن کاملThe Role of Escherichia coli Porins OmpC and OmpF in Antibiotic Cross Resistance Induced by Sub-Lethal Levels of Kanamycin
Previous studies have shown that pretreatment of E. coli with low doses of kanamycin have generated an increase in the resistance to high doses of kanamycin as well as induced cross resistance to a broad range of unrelated antibiotics, and that multiantibiotic-resistant E. coli had lower levels of OmpF porin. In this study, the role of OmpC and OmpF porins in the development of cross resistance...
متن کاملThe Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC.
We performed transposon mutagenesis of a two-color fluorescent reporter strain to identify new regulators of the porin genes ompF and ompC in Escherichia coli. Screening of colonies by fluorescence microscopy revealed numerous mutants that exhibited interesting patterns of porin expression. One mutant harbored an insertion in the gene encoding the histidine kinase CpxA, the sensor for a two-com...
متن کاملPermeation of antibiotics through Escherichia coli OmpF and OmpC porins: screening for influx on a single-molecule level.
A chip-based automated patch-clamp technique provides an attractive biophysical tool to quantify solute permeation through membrane channels. Proteo-giant unilamellar vesicles (proteo-GUVs) were used to form a stable lipid bilayer across a micrometer-sized hole. Because of the small size and hence low capacitance of the bilayer, single-channel recordings were achieved with very low background n...
متن کاملThe role of OmpC and OmpF in acidic resistance in Escherichia coli.
The roles of OmpC and OmpF in acidic resistance (AR) were examined. When ompC and ompF were deleted, AR was decreased. The decreased level of AR seen in the mutant that was deficient in ompC and ompF was elevated by the addition of glutamate, but not by the addition of arginine or lysine. The expression levels of adiA and cadB were diminished by the deletion of ompC and ompF, and the conversion...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1994
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.62.4.1236-1240.1994